Typical question of the current zeitgeist, but fundamentally a category error.
"Europeans", past or present, are not a group of people that have a collective agency in the way that individuals do. Some groups (like political parties, governments, companies, associations, etc...) can be considered to behave as single deliberate actors over some timeframes for some purposes, but "Europeans" cannot. It's too broad, too diverse, too disparate, and too disunified a set of people. As such, it is not a group that is capable of doing something wilful and, because almost all definitions of genocide require intent, cannot commit genocide. To make an imperfect analogy: it's like asking if a tornado is a serial killer, or rather (because there's no temporal limit on which Europeans are being considered) if tornadoes in general are murders. It's not a question that can be answered, because it doesn't make sense semantically.
Now if you want to ask about specific companies or expeditions of conquistadors, or specific Spanish (and later American) governments deliberately carried out incremental steps of genocide, then that's a whole other question. But just because a label might apply to a narrow group of people, doesn't mean that it's wise to apply it a much broader group of people just because it includes the former. Especially with emotionally charged terms like genocide.